Northwestern University Feinberg School of Medicine

Scleroderma Program

John  Varga, MD

John Varga, MD

Director, Northwestern Scleroderma

John and Nancy Hughes Distinguished Professor of Rheumatology

Professor of Medicine (Rheumatology), Dermatology and Pharmacology

Focus of Work

Bio

Our research focuses on fibrosis and tissue repair. Fibrosis and aberrant tissue repair are prominent in autoimmune diseases (scleroderma, myositis, lupus) and in organ-based disorders (pulmonary fibrosis, glomerulosclerosis, hypertrophic scar), and are considered intractable. Aberrant tissue regeneration also underlie aging and obesity. Fibrosis contributes to 30% of all death worldwide, and thus represents a compelling and urgent scientific challegen.
We believe that fibrosis is in fact potent...[Read full text]
Our research focuses on fibrosis and tissue repair. Fibrosis and aberrant tissue repair are prominent in autoimmune diseases (scleroderma, myositis, lupus) and in organ-based disorders (pulmonary fibrosis, glomerulosclerosis, hypertrophic scar), and are considered intractable. Aberrant tissue regeneration also underlie aging and obesity. Fibrosis contributes to 30% of all death worldwide, and thus represents a compelling and urgent scientific challegen.
We believe that fibrosis is in fact potentially reversible. Our research takes a "systems-biology" multi-disciplinary approach to fibrosis, utilizing human tissue, DNA, serum, and animal models and cell biology studies to identify and validate novel targets for therapy, discover genetic risk factors and useful biomarkers. we then attempt to translate these discoveries into clinically relevant approaches.[Shorten text]

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Education and Certification

  • MD: New York U (1980)
  • Residency: Rhode Island Hospital (1983)
  • Fellowship: Boston University Medical Center (1985)
  • Board Certification: Internal Medicine, Rheumatology

Northwestern Scholars

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